個人簡介:
張紅星,女,醫(yī)學(xué)博士,教授、主任醫(yī)師,碩士生導(dǎo)師,馬來西亞理科大學(xué)聯(lián)合培養(yǎng)博士生導(dǎo)師,從事精神疾病生物學(xué)機制與臨床相關(guān)研究。曾獲得“全國衛(wèi)生系統(tǒng)先進(jìn)個人,教育部新世紀(jì)優(yōu)秀人才、中原英才系列-中原科技領(lǐng)軍人才,河南省科技創(chuàng)新杰出青年、河南省學(xué)術(shù)技術(shù)帶頭人、河南省優(yōu)秀中青年衛(wèi)生科技創(chuàng)新人才,河南省師德先進(jìn)個人,河南省教育廳學(xué)術(shù)技術(shù)帶頭人、河南省醫(yī)學(xué)學(xué)術(shù)技術(shù)帶頭人”等稱號。中國神經(jīng)科學(xué)學(xué)會精神病學(xué)基礎(chǔ)與臨床分會委員,河南省醫(yī)學(xué)會精神科專業(yè)委員會常委,河南省心理衛(wèi)生協(xié)會常務(wù)理事,河南省醫(yī)學(xué)科學(xué)普及精神衛(wèi)生分會常務(wù)委員。
主持國家自然科學(xué)基金面上項目3項,國家重點研發(fā)項目課題1項,教育部新世紀(jì)優(yōu)秀人才支持計劃1項,省級項目6項,獲河南省科技進(jìn)步獎三等獎1項,以第一作者或通訊作者發(fā)表論文64篇,其中SCI期刊源論文27篇;參編教材7部。
教育與工作經(jīng)歷:
1997.07-2001.09 河南省衛(wèi)生學(xué)校 藥理教研室教師,從事臨床藥物學(xué)教學(xué)工作;
2007.06-2009.07 新鄉(xiāng)醫(yī)學(xué)院第二附屬醫(yī)院(河南省精神病醫(yī)院)臨床心理
科醫(yī)生,副教授
2009.07-2013.11 新鄉(xiāng)醫(yī)學(xué)院第二附屬醫(yī)院(河南省精神病醫(yī)院)科教科,
副主任醫(yī)師/副教授,科教科科長;
2013.11-至今 新鄉(xiāng)醫(yī)學(xué)院心理學(xué)院,教授/主任醫(yī)師,心理學(xué)院
聯(lián)系方式:
Zhx166666@163.com
研究興趣及方向:
精神癥狀認(rèn)知生理心理機制
主要學(xué)術(shù)職務(wù)與榮譽稱號:
1.教育部新世紀(jì)優(yōu)秀人才 2012
2.河南省教育廳學(xué)術(shù)技術(shù)帶頭人 2012
3.河南省衛(wèi)生廳:河南省衛(wèi)生科技管理先進(jìn)個人,2012年2月
4.全國衛(wèi)生系統(tǒng)先進(jìn)工作者 中華人民共和國人力資源和社會保障部、衛(wèi)生部和國家中醫(yī)藥管理局2012.9
5.河南省優(yōu)秀中青年衛(wèi)生科技創(chuàng)新人才 2012.9.27
6.河南省師德先進(jìn)個人 2016
7.河南省學(xué)術(shù)技術(shù)帶頭人 2016
8.河南省科技創(chuàng)新人才杰出青年 2016
9.河南省文明教師2019
10.中原千人計劃:河南省科技創(chuàng)新領(lǐng)軍人才2019.12
11.河南省高層次人才2020
12.河南省衛(wèi)生科技創(chuàng)新型人才工程中青年科技創(chuàng)新人才 2015
研究項目:
1.2011,國家自然科學(xué)基金,基因功能SNPs與DNA甲基化共同影響精神分裂癥易感性機制研究,81071091
2.2015,國家自然科學(xué)基金,電休克刺激對SD大鼠腦中樞神經(jīng)系統(tǒng)可塑性的影響(81571315),2016.01-2017.12.
3.2017,國家重點研發(fā)計劃資助(2016YFC1306700)抑郁障礙臨床診斷、干預(yù)與轉(zhuǎn)歸的客觀標(biāo)記物研究(2016YFC1306704),2016 年07 月 —— 2020 年12 月,77萬元 課題四:MDD發(fā)病和復(fù)發(fā)風(fēng)險評估模型及診斷工具包開發(fā)應(yīng)用
4.2017年申報,河南省高校科技創(chuàng)新團隊,精神疾病認(rèn)知生理心理機制研究團隊(18IRTSTHN025):2018.01-2019.12
5.2017,國家自然科學(xué)基金-河南省聯(lián)合基金重點培育項目。多維度關(guān)聯(lián)分析腦白質(zhì)功能相關(guān)基因篩選精神分裂癥生物學(xué)標(biāo)記(U1704190),L02,,2018.01.01-2020.12.31
6.中共河南省委組織部,河南省人力資源和社會保障廳 中原千人計劃-中原科技創(chuàng)新領(lǐng)軍人才。基于認(rèn)知圖式的冷執(zhí)行功能訓(xùn)練對抑郁癥患者的康復(fù)作用及腦影像學(xué)機制204200510020,2020.01.01-2022.12.31 Zhongyuan One Thouthand Talents Program (204200510020)
7.2011,新世紀(jì)優(yōu)秀人才支持計劃,基于全基因組DNA甲基化篩選基礎(chǔ)上的精神分裂癥患者目的基因甲基化狀態(tài)檢測,NCET-10-0137, 2010.01-2014.12,50萬.
8.2018 河南省科技創(chuàng)新人才(杰出青年)計劃174100510024,基于匯聚功能基因組學(xué)信息建立精神分裂癥遺傳影像學(xué)聯(lián)合診斷標(biāo)記. 2017.01-2018.12, 30萬.
9.2010,河南省科技廳發(fā)展計劃,基因功能SNPs與DNA甲基化共同影響精神分裂癥易感性機制研究,102102310153. 2010.01-2012.12
10.2008,河南省科技廳發(fā)展計劃,Neuregulin-1基因多態(tài)性及其功能表達(dá)與精神分裂癥,08210230081,2009.01-2011.12
11.2010,河南省高校青年骨干教師,候選基因甲基化狀態(tài)與精神分裂癥的關(guān)聯(lián)研究,2010GGJS-116,2010.01-2012.12.
12.2012,河南省醫(yī)學(xué)學(xué)術(shù)技術(shù)帶頭人出國研修項目:精神分裂癥患者主動式社區(qū)康復(fù)模式探索,河南省衛(wèi)生廳,10.29萬.。2012.01-2013.01
13.2013,河南省衛(wèi)生廳 河南衛(wèi)生科技創(chuàng)新型人才工程優(yōu)秀人員項目,精神疾病全基因組關(guān)聯(lián)分析與藥物基因組學(xué)研究(cxyx20130418). 2013.01-2015.12
14.主動式社區(qū)康復(fù)模式下慢性精神疾病患者心理干預(yù)模式探索,2014-GH-643 完成時間:2015.04
15.2015,河南省科技廳,電休克剌激對精神分裂癥模型大鼠腦神經(jīng)元網(wǎng)絡(luò)振蕩的影響,(152300410122),2015.01-2017.12. 5萬元
學(xué)術(shù)論文與專著:
1.Hong-Xing Zhang, Zhao JP, Lv LX, Li WQ, Xu L, Ouyang X, Yuan ZQ, Huang JS. Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia. Neuroscience letters 2008 24(5):1-5.(IF=2.2)ISSN:0304-3940
2.Li W, Wang X, Zhao J, Lin J, Song X, Yang Y, Jiang C, Xiao B, Yang G, Zhang H*(通訊作者), Lv L*. Association Study of myelin transcription factor 1-like polymorphisms with schizophrenia in Han Chinese population. Genes Brain Behav. 2012 Feb;11(1):87-93.. (IF=4.061)ISSN:1601-1848
3.Yanshen Jiang, Hongxing Zhang*, Zifan Wang, Ling Zhao, Luxian Lv*. Effects of modified electroconvulsive therapy on the cognitive function and blood parameters in female patients with schizophrenia Int ernational Journal of Clinical and Experimental Medicine Int J Clin Med.2015;8(1):1349-1355 ISSN 1940-5901. (IF=1.277)
4.Zhao Ling, Jiang Yansheng, Zhang Hongxing*. Effects of modified electroconvulsive therapy on the electroencephalogram of schizophrenia patients. SpringerPlus2016;5(1): 1063. ISSN: 2193-1801(IF=0.982)
5.Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai,Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang*, Chunming Xie*, Zhijun Zhang. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of Psychiatric Research. 2017 Jan;84:9-17. ISSN:0022-3956(IF=4.465)
6.Yi Yu, Yun Zhao, Yajing Si, Qiongqiong Ren, Wu Ren, Changqin Jing and Hongxing Zhang*. Estimation of the cool executive function using frontal electroencephalogram signals in first?episode schizophrenia patients. BioMed Eng OnLine 2016 Nov 25;15(1):131-145 ISSN: 1475-925X (IF=1.682)
7.Liang Gong, Cancan He, Haisan Zhang, Hongxing Zhang*, Zhijun Zhang, Chunming Xie*. Disrupted reward and cognitive control networks contribute to anhedonia in depression, Psychiatry research. J Psychiatr Res. 2018 Aug;103:61-68. doi: 10.1016/j.jpsychires.2018.05.010. Epub 2018 May 12.
8.He C, Gong L, Yin Y, Yuan Y, Zhang H, Lv L, Zhang X, Soares JC, Zhang H, Xie C, Zhang Z. Amygdala connectivity mediates the association between anxiety and depression in patients with major depressive disorder. Brain Imaging Behav. 2019;13(4):1146-1159. doi: 10.1007/s11682-018-9923-z.IF=3.391
9.Li, K., Zhang, H., Wang, B., Yang, Y., Zhang, M., Li, W., Li, X., Lv, L., Zhao, J., & Zhang, H. (2020). Hippocampal functional network: The mediating role between obsession and anxiety in adult patients with obsessive-compulsive disorder. The world journal of biological psychiatry., 2020 Nov;21(9):685-695. doi: 10.1080/15622975.2020.1733082. Epub 2020 Mar 16. IF2020=4.132
10.Kun Li# , Haisan Zhang# , Yongfeng Yang, Jianli Zhu , Bi Wang , Yanli Shi , Xianrui Li,,Meng Zhang, Luxian Lv ?, Hongxing Zhang*, Abnormal functional network of the thalamic subregions in adult patients with obsessive-compulsive disorder, Behavioural Brain Research, 2019 May 26;371:111982. IF=3.327 ISSN : 0166-4328
11.Xianrui Li, Meng Zhang, Kun Li, Feng Zou, Yufeng Wang, Xin Wu and Hongxing Zhang* The Altered Somatic Brain Network in State Anxiety. Frontier in Psychiatry.2019,07 IF=3.161 ISSN: 1664-0640
12.Haisan Zhang, Bi Wang, Kun Li, Xiaoyue Wang, Xianrui Li, Jianli Zhu, Qingjiang Zhao, Yongfeng Yang, Luxian Lv, Meng Zhang and Hongxing Zhang*.Altered Functional Connectivity Between the Cerebellum and the Cortico-Striato-Thalamo-Cortical Circuit in Obsessive-Compulsive Disorder. Frontier in Psychiatry. 2019.07, 10:522 P1-8. IF=3.161 ISSN: 1664-0640
13.Li K, Zhang M, Zhang H, Li X, Zou F, Wang Y, Wu X, Zhang H*.The spontaneous activity and functional network of the occipital cortex is correlated with state anxiety in healthy adults. Neurosci Lett. Neurosci Lett. 2020;715:134596. doi:10.1016/j.neulet.2019.134596 IF2020=3.046
14.Zhijun Zhang #, Hongxing Zhang # , Chun-Ming Xie # , Meng Zhang # , Yachen Shi , Ruize Song , Xiang Lu , Haisan Zhang , Kun Li , Bi Wang , Yongfeng Yang , Xianrui Li , Jianli Zhu , Yang Zhao , Ti-Fei Yuan , Georg Northoff. Task-related functional magnetic resonance imaging-based neuronavigation for the treatment of depression by individualized repetitive transcranial magnetic stimulation of the visual cortex. Sci China Life Sci. 2021 Jan;64(1):96-106. IF=6.03
15.Xinyi Liu , Cancan He , Dandan Fan , Yao Zhu , Feifei Zang , Qing Wang , Haisan Zhang , Zhijun Zhang , Hongxing Zhang *, Chunming Xie * Disrupted rich-club network organization and individualized identification of patients with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2020 Aug 18;110074. IF=4.263
16.Xiaoxiao Shan Haisan Zhang Zhao Dong indong Chen Feng Liu5 Jingping Zhao Hongxing Zhang Wenbin Guo. Increased subcortical region volume induced by electroconvulsive therapy in patients with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 2021 Oct;271(7):1285-1295. doi: 10.1007/s00406-021-01303-6. Epub 2021 Jul 17. IF2021=5.760
17.Tong W, Dong Z, Guo W, Zhang M, Zhang Y, Du Y, Zhao J, Lv L, Liu Y, Wang X, Kou Y, Zhang H, Zhang H. Progressive Changes in Brain Regional Homogeneity Induced by Electroconvulsive Therapy Among Patients With Schizophrenia. J ECT. 2022 Jun 1;38(2):117-123. doi: 10.1097/YCT.0000000000000815. PMID: 35613010. IF= 3.692 ISSN:1095-0680
18.Liu Y, Zhang J, Zhang M, Li X, Li K, Wang B, Yang Y, Song R, Si Y, Ni T, Wang X, Geng Y, Chang Q, Zhang H, Zhang Z, Zhang H. Abnormal brain gray matter volume in patients with major depressive disorder: Associated with childhood trauma? J Affect Disord. 2022 Apr 20;308:562-568. (IF2022=6.533) ISSN:0165-0327
19.Si Y, Liu C, Kou Y, Dong Z, Zhang J, Wang J, Lu C, Luo Y, Ni T, Du Y, Zhang H.Antipsychotics-induced improvement of cool executive function in individuals living with schizophrenia. Front Psychiatry. 2023 Apr 27;14:1154011.
20.Si Y, Li P, Wang X, Yao G, Liu C, Liu Y, Zhang J, Zhang H, Luo Y. Cueing effect of attention among nurses with different anxiety levels: an EEG study. Med Biol Eng Comput. 2023 Mar 29.