教 學(xué) 科 研 成 果 及 榮 譽(yù) |
主持科研項(xiàng)目: 1．2011，國家自然科學(xué)基金，基因功能SNPs與DNA甲基化共同影響精神分裂癥易感性機(jī)制研究，81071091. 2．2017．國家科技部，國家重點(diǎn)研發(fā)計(jì)劃資助(2016YFC1306700)：抑郁障礙臨床診斷、干預(yù)與轉(zhuǎn)歸的客觀標(biāo)記物研究（2016YFC1306704），2016 年07 月 —— 2020 年12 月，77萬元 課題四：MDD發(fā)病和復(fù)發(fā)風(fēng)險(xiǎn)評估模型及診斷工具包開發(fā)應(yīng)用. 3．2015．國家自然科學(xué)基金，電休克刺激對SD大鼠腦中樞神經(jīng)系統(tǒng)可塑性的影響（81571315），2016.01-2017.12. 4．2017，國家自然科學(xué)基金-河南省聯(lián)合基金重點(diǎn)培育項(xiàng)目。多維度關(guān)聯(lián)分析腦白質(zhì)功能相關(guān)基因篩選精神分裂癥生物學(xué)標(biāo)記(U1704190)，L02，2018.01.01-2020.12.31. 5．2011，新世紀(jì)優(yōu)秀人才支持計(jì)劃，基于全基因組DNA甲基化篩選基礎(chǔ)上的精神分裂癥患者目的基因甲基化狀態(tài)檢測，NCET-10-0137. 6．2019，中共河南省委組織部，河南省人力資源和社會(huì)保障廳 中原千人計(jì)劃-中原科技創(chuàng)新領(lǐng)軍人才?；谡J(rèn)知圖式的冷執(zhí)行功能訓(xùn)練對抑郁癥患者的康復(fù)作用及腦影像學(xué)機(jī)制204200510020，2020.01.01-2022.12.31. 7．2018 河南省科技創(chuàng)新人才（杰出青年）計(jì)劃174100510024，基于匯聚功能基因組學(xué)信息建立精神分裂癥遺傳影像學(xué)聯(lián)合診斷標(biāo)記. 2017.01-2018.12, 30萬. 8．2010，河南省科技廳發(fā)展計(jì)劃，基因功能SNPs與DNA甲基化共同影響精神分裂癥易感性機(jī)制研究，102102310153. 9．2008，河南省科技廳發(fā)展計(jì)劃，Neuregulin-1基因多態(tài)性及其功能表達(dá)與精神分裂癥，08210230081. 10．2010，河南省高校青年骨干教師，候選基因甲基化狀態(tài)與精神分裂癥的關(guān)聯(lián)研究，2010GGJS-116. 11．2010，河南省教育廳自然科學(xué)基金，基因組DNA甲基化水平與精神分裂癥關(guān)聯(lián)研究，2010A320014. 12．2012.01-2013.01精神分裂癥患者主動(dòng)式社區(qū)康復(fù)模式探索，河南省衛(wèi)生廳，5.0. 13．2013－01－2015.12 河南省衛(wèi)生廳 河南衛(wèi)生科技創(chuàng)新型人才工程優(yōu)秀人員項(xiàng)目，精神疾病全基因組關(guān)聯(lián)分析與藥物基因組學(xué)研究（cxyx20130418）. 14．2014，主動(dòng)式社區(qū)康復(fù)模式下慢性精神疾病患者心理干預(yù)模式探索，2014-GH-643 完成時(shí)間：2015.04. 15．2015,河南省科技廳，電休克剌激對精神分裂癥模型大鼠腦神經(jīng)元網(wǎng)絡(luò)振蕩的影響，（152300410122），2015.01-2017.12. 5萬元. 16．2016，PN-KFKT-10 張紅星 多維度關(guān)聯(lián)分析腦白質(zhì)功能相關(guān)基因篩選精神分裂癥生物學(xué)標(biāo)記，精神神經(jīng)研究院開放課題,10萬元. 17．2017年申報(bào)，河南省高?？萍紕?chuàng)新團(tuán)隊(duì)，精神疾病認(rèn)知生理心理機(jī)制研究團(tuán)隊(duì)（18IRTSTHN025）：2018.01-2019.12. 發(fā)表SCI期刊論文： 1．Hong-Xing Zhang, Zhao JP, Lv LX, Li WQ, Xu L, Ouyang X, Yuan ZQ, Huang JS. Explorative study on the expression of neuregulin-1 gene in peripheral blood of schizophrenia. Neuroscience letters 2008 24(5):1-5.（IF=2.2）ISSN:0304-3940 2．Li W, Wang X, Zhao J, Lin J, Song X, Yang Y, Jiang C, Xiao B, Yang G, Zhang H*（通訊作者）, Lv L*. Association Study of myelin transcription factor 1-like polymorphisms with schizophrenia in Han Chinese population. Genes Brain Behav. 2012 Feb;11(1):87-93.. （IF=4.061）ISSN:1601-1848 3．Liang Gong, Yingying Yin, Cancan He, Qing Ye, Feng Bai,Yonggui Yuan, Haisan Zhang, Luxian Lv, Hongxing Zhang*, Chunming Xie*, Zhijun Zhang. Disrupted reward circuits is associated with cognitive deficits and depression severity in major depressive disorder. Journal of Psychiatric Research. 2017 Jan;84:9-17. ISSN:0022-3956（IF=4.465） 4．Yi Yu, Yun Zhao, Yajing Si, Qiongqiong Ren, Wu Ren, Changqin Jing and Hongxing Zhang*. Estimation of the cool executive function using frontal electroencephalogram signals in first?episode schizophrenia patients. BioMed Eng OnLine 2016 Nov 25;15(1):131-145 ISSN: 1475-925X (IF=1.682) 5．Liang Gong, Cancan He, Haisan Zhang, Hongxing Zhang*, Zhijun Zhang, Chunming Xie*. Disrupted reward and cognitive control networks contribute to anhedonia in depression, Psychiatry research. J Psychiatr Res. 2018 Aug;103:61-68. doi: 10.1016/j.jpsychires.2018.05.010. Epub 2018 May 12. 6．He C, Gong L, Yin Y, Yuan Y, Zhang H, Lv L, Zhang X, Soares JC, Zhang H*, Xie C, Zhang Z. Amygdala connectivity mediates the association between anxiety and depression in patients with major depressive disorder. Brain Imaging Behav. 2019;13(4):1146-1159. doi: 10.1007/s11682-018-9923-z.IF=3.391 7．Li, K., Zhang, H., Wang, B., Yang, Y., Zhang, M., Li, W., Li, X., Lv, L., Zhao, J., & Zhang, H*. (2020). Hippocampal functional network: The mediating role between obsession and anxiety in adult patients with obsessive-compulsive disorder. The world journal of biological psychiatry., 2020 Nov;21(9):685-695. doi: 10.1080/15622975.2020.1733082. Epub 2020 Mar 16. IF2020=4.132 8．Kun Li# , Haisan Zhang# , Yongfeng Yang, Jianli Zhu , Bi Wang , Yanli Shi , Xianrui Li,,Meng Zhang, Luxian Lv ?, Hongxing Zhang*, Abnormal functional network of the thalamic subregions in adult patients with obsessive-compulsive disorder, Behavioural Brain Research, 2019 May 26;371:111982. IF=3.327 ISSN : 0166-4328 9．Xianrui Li, Meng Zhang, Kun Li, Feng Zou, Yufeng Wang, Xin Wu and Hongxing Zhang* The Altered Somatic Brain Network in State Anxiety. Frontier in Psychiatry.2019,07 IF=3.161 ISSN: 1664-0640 10．Haisan Zhang, Bi Wang, Kun Li, Xiaoyue Wang, Xianrui Li, Jianli Zhu, Qingjiang Zhao, Yongfeng Yang, Luxian Lv, Meng Zhang and Hongxing Zhang*.Altered Functional Connectivity Between the Cerebellum and the Cortico-Striato-Thalamo-Cortical Circuit in Obsessive-Compulsive Disorder. Frontier in Psychiatry. 2019．07， 10:522 P1-8. IF=3.161 ISSN: 1664-0640 11．Li K, Zhang M, Zhang H, Li X, Zou F, Wang Y, Wu X, Zhang H*.The spontaneous activity and functional network of the occipital cortex is correlated with state anxiety in healthy adults. Neurosci Lett. Neurosci Lett. 2020;715:134596. doi:10.1016/j.neulet.2019.134596 IF2020=3.046 12．Zhijun Zhang #, Hongxing Zhang # , Chun-Ming Xie # , Meng Zhang # , Yachen Shi , Ruize Song , Xiang Lu , Haisan Zhang , Kun Li , Bi Wang , Yongfeng Yang , Xianrui Li , Jianli Zhu , Yang Zhao , Ti-Fei Yuan , Georg Northoff. Task-related functional magnetic resonance imaging-based neuronavigation for the treatment of depression by individualized repetitive transcranial magnetic stimulation of the visual cortex. Sci China Life Sci. 2021 Jan;64(1):96-106. IF=6.03 13．Xinyi Liu , Cancan He , Dandan Fan , Yao Zhu , Feifei Zang , Qing Wang , Haisan Zhang , Zhijun Zhang , Hongxing Zhang *, Chunming Xie * Disrupted rich-club network organization and individualized identification of patients with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry. 2020 Aug 18;110074. IF=4.263 14．Xiaoxiao Shan Haisan Zhang Zhao Dong Chen Feng Liu5 Jingping Zhao Hongxing Zhang* Wenbin Guo. Increased subcortical region volume induced by electroconvulsive therapy in patients with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 2021 Oct;271(7):1285-1295. doi: 10.1007/s00406-021-01303-6. Epub 2021 Jul 17. IF2021=5.760 15．Tong W, Dong Z, Guo W, Zhang M, Zhang Y, Du Y, Zhao J, Lv L, Liu Y, Wang X, Kou Y, Zhang H, Zhang H*. Progressive Changes in Brain Regional Homogeneity Induced by Electroconvulsive Therapy Among Patients With Schizophrenia. J ECT. 2022 Jun 1;38(2):117-123. doi: 10.1097/YCT.0000000000000815. PMID: 35613010. IF= 3.692 ISSN：1095-0680 16．Liu Y, Zhang J, Zhang M, Li X, Li K, Wang B, Yang Y, Song R, Si Y, Ni T, Wang X, Geng Y, Chang Q, Zhang H, Zhang Z, Zhang H*. Abnormal brain gray matter volume in patients with major depressive disorder: Associated with childhood trauma? J Affect Disord. 2022 Apr 20;308:562-568. (IF2022=6.533) ISSN：0165-0327 17．Si Y, Liu C, Kou Y, Dong Z, Zhang J, Wang J, Lu C, Luo Y, Ni T, Du Y, Zhang H.Antipsychotics-induced improvement of cool executive function in individuals living with schizophrenia. Front Psychiatry. 2023 Apr 27;14:1154011. 18．Si Y, Li P, Wang X, Yao G, Liu C, Liu Y, Zhang J, Zhang H, Luo Y. Cueing effect of attention among nurses with different anxiety levels: an EEG study. Med Biol Eng Comput. 2023 Mar 29. |
