程彬峰，男，1985年出生。博士，副教授，碩士研究生導(dǎo)師。

聯(lián)系方式

E-mail：chengbinfeng@xxmu.edu.cn

教育與工作經(jīng)歷

2013.07---至今新鄉(xiāng)醫(yī)學(xué)院，生命科學(xué)技術(shù)學(xué)院，應(yīng)用神經(jīng)科學(xué)研究所

2008.09-2013.06  南開(kāi)大學(xué)，藥學(xué)院，博士（碩博連讀）

2004.09-2008.07河南師范大學(xué)，生命科學(xué)學(xué)院，學(xué)士

研究方向

神經(jīng)炎癥與保護(hù)；干細(xì)胞分化與治療；中藥抗炎與免疫

項(xiàng)目課題

1、國(guó)家自然基金青年基金項(xiàng)目，基于VEGF/MAPK/FAK通路調(diào)控的風(fēng)濕骨痛膠囊通絡(luò)止痛的機(jī)制研究，81403161，2015.01-2017.12，主持。

2、河南省高等學(xué)校重點(diǎn)科研項(xiàng)目，NCAM抑制MSCs軟骨肥大的作用及其治療骨關(guān)節(jié)炎的開(kāi)發(fā)應(yīng)用研究，19A310020，2019.01-2020.12，主持。

3、新鄉(xiāng)醫(yī)學(xué)院博士啟動(dòng)基金，神經(jīng)細(xì)胞粘附分子對(duì)骨髓間充質(zhì)干細(xì)胞向軟骨分化的調(diào)控作用及機(jī)制，主持。

代表性成果

1、Gao YX, Yu HH, He C, Li M, Guo DD, Lian JJ, Yang HJ, Wang M, Wang L*, Feng ZW, Cheng BF*. Fengshi Gutong capsule attenuates osteoarthritis by inhibiting MAPK, NF-κB, AP-1, and Akt pathways. Front Pharmacol, 2018, 9:910.

2、Ma J, Gao SS, Yang HJ, Wang M, Cheng BF*, Feng ZW, Wang L*. Neuroprotective effects of proanthocyanidins, natural flavonoids derived from plants, on rotenone-induced oxidative stress and apoptotic cell death in human neuroblastoma SH-SY5Y cells. Front Neurosci, 2018, 12:369.

3、Cheng BF, Gao YX, Lian JJ, Guo DD, Liu TT, Xie YF, Wang L, Yang HJ, Wang M*, Feng ZW. Anti-inflammatory effects of pitavastatin in interleukin-1β-induced SW982 human synovial cells. Int Immunopharmacol, 2017, 50:224-229.

4、Yao-Xin Gao, Bin-Feng Cheng*, Jun-Jiang Lian, Dan-Dan Guo, Jing-Wen Qin, Yong-Bo Zhang, Hai-Jie Yang, Mian Wang, Lei Wang*, Zhi-Wei Feng.Liquiritin, a flavone compound from licorice, inhibits IL-1β-induced inflammatory responses in SW982 human synovial cells. J Funct Foods, 2017, 33: 142-148.

5、Bin-Feng Cheng, Yao-Xin Gao, Jun-Jiang Lian, Dan-dan Guo, Lei Wang*, Mian Wang, Hai-Jie Yang* and Zhi-Wei Feng. Hydroxysafflor yellow A inhibits IL-1β-induced release of IL-6, IL-8, and MMP-1 via suppression of ERK, NF-κB and AP-1 signaling in SW982 human synovial cells. Food Funct, 2016, 7: 4516-4522.

6、Jun-Jiang Lian, Bin-Feng Cheng*, Yao-Xin Gao, Han Xue, Lei Wang, Mian Wang, Hai-Jie Yang, Zhi-Wei Feng*. Protective effect of kaempferol, a flavonoid widely present in varieties of edible plants, on IL-1β-induced inflammatory response via inhibiting MAPK, Akt, and NF-κB signalling in SW982 cells. J Funct Foods, 2016, 27: 214-222.

7、連俊江，程彬峰*，高堯鑫，張亞平，馬雙平，張彬彬，郭丹丹，薛寒，馮志偉。齊墩果酸對(duì)IL-1β誘導(dǎo)的SW982細(xì)胞炎癥反應(yīng)的抑制作用。藥學(xué)學(xué)報(bào)，第51卷，第11期，1711-1716頁(yè)。