莊婷,1983.01-,本科畢業(yè)于山東大學(xué)醫(yī)學(xué)院臨床醫(yī)學(xué)專(zhuān)業(yè),碩士畢業(yè)于山東大學(xué)醫(yī)學(xué)院病理學(xué)專(zhuān)業(yè),2015年獲得瑞典卡羅林斯卡醫(yī)學(xué)院博士學(xué)位。2018年被授予新鄉(xiāng)醫(yī)學(xué)院“太行青年學(xué)者”稱(chēng)號(hào)。目前研究方向?yàn)槟[瘤學(xué),主要從事乳腺癌發(fā)病機(jī)制的相關(guān)研究。主持國(guó)家自然科學(xué)基金1項(xiàng),河南省教育廳基金1項(xiàng);在Nature Communications、Oncogene、Oncogenesis、J Exp Clin Cancer Res. 等雜志上發(fā)表SCI論文17篇。 代表性SCI論文一覽表(#為第一作者,*為通訊作者) Costa TDF, Zhuang T, Lorent J, Turco E, Olofsson H, Masia-Balague M, Zhao M, Rabieifar P, Robertson N, Kuiper R, Sj?lund J, Spiess M, Hernández-Varas P, Rabenhorst U, Roswall P, Ma R, Gong X, Hartman J, Pietras K, Adams PD, Defilippi P, Str?mblad S. PAK4 suppresses RELB to prevent senescence-like growth arrest in breast cancer.Nat Commun. 2019 Aug 9;10(1):3589.IF=11.878 Xue M, Zhang K, Mu K, Xu J, Yang H, Liu Y, Wang B, Wang Z, Li Z, Kong Q, Li X*, Wang H*, Zhu J*, Zhuang T*. Regulation of estrogen signaling and breast cancer proliferation by an ubiquitin ligase TRIM56. Oncogenesis. 2019 Apr 18;8(5):30. IF=5.995 Hou Y, Li X, Li Q, Xu J, Yang H, Xue M, Niu G, Zhuo S, Mu K, Wu G, Li X*, Wang H*, Zhu J*, Zhuang T*. STAT1 facilitates oestrogen receptor α transcription and stimulates breast cancer cell proliferation.J Cell Mol Med. 2018 Dec;22(12):6077-6086.IF=4.658 Liu Z, Zhang J, Xu J, Yang H, Li X, Hou Y, Zhao Y, Xue M, Wang B, Yu N, Yu S, Niu G, Wu G, Li X*, Wang H*, Zhu J*, Zhuang T*. RNF168 facilitates oestrogen receptor ɑ transcription and drives breast cancer proliferation.J Cell Mol Med. 2018 Sep;22(9):4161-4170.IF=4.658 Yang H, Yu N, Xu J, Ding X, Deng W, Wu G, Li X, Hou Y, Liu Z, Zhao Y, Xue M, Yu S, Wang B, Li X, Niu G, Wang H*, Zhu J*, Zhuang T*. SMURF1 facilitates estrogen receptor ɑ signaling in breast cancer cells.J Exp Clin Cancer Res. 2018 Feb 12;37(1):24.IF=5.646 Zhuang T#, Yu S#, Zhang L#, Yang H, Li X, Hou Y, Liu Z, Shi Y, Wang W, Yu N, Li A, Li X, Li X, Niu G, Xu J, Hasni MS, Mu K, Wang H, Zhu J. SHARPIN stabilizes estrogen receptor α and promotes breast cancer cell proliferation.Oncotarget. 2017 Aug 19;8(44):77137-77151. Yang H, Yu S, Wang W, Li X, Hou Y, Liu Z, Shi Y, Mu K, Niu G, Xu J, Wang H*, Zhu J*, Zhuang T*. SHARPIN Facilitates p53 Degradation in Breast Cancer Cells.Neoplasia. 2017 Feb;19(2):84-92.IF=4.994 Zhuang T#, Zhu J#, Li Z, Lorent J, Zhao C, Dahlman-Wright K, Str?mblad S. p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cells.Oncotarget. 2015 Dec 22;6(41):43853-68.
主持的科研項(xiàng)目: Smurf1蛋白調(diào)節(jié)乳腺癌雌激素信號(hào)通路的機(jī)制研究,莊婷,國(guó)家自然科學(xué)基金, 2018.01-2020.12,No. 81702725,20萬(wàn)元; SHARPIN蛋白調(diào)控乳腺癌p53泛素化降解的新機(jī)制,莊婷,河南省高等學(xué)校重點(diǎn)科研項(xiàng)目,2017.01-2018.12,No. 17A310025,3萬(wàn)元
指導(dǎo)學(xué)生獲得的獎(jiǎng)項(xiàng): 中華醫(yī)學(xué)會(huì)第十五次全國(guó)檢驗(yàn)醫(yī)學(xué)學(xué)術(shù)會(huì)議研究生擂臺(tái)賽(碩士組)【一等獎(jiǎng)】(2019.08) 全國(guó)醫(yī)科院校研究生聯(lián)盟2019年暑期研究生論壇【三等獎(jiǎng)】(2019.07) 第十三屆“挑戰(zhàn)杯”新鄉(xiāng)醫(yī)學(xué)院大學(xué)生課外學(xué)術(shù)科技作品競(jìng)賽【一等獎(jiǎng)】(2019.04) 第十三屆“挑戰(zhàn)杯”新鄉(xiāng)醫(yī)學(xué)院大學(xué)生課外學(xué)術(shù)科技作品競(jìng)賽【二等獎(jiǎng)】(2019.04) 第二屆全國(guó)臨床檢驗(yàn)診斷學(xué)研究生學(xué)術(shù)論文競(jìng)賽【特等獎(jiǎng)】(2018.04) 第十五屆“挑戰(zhàn)杯”全國(guó)大學(xué)生課外學(xué)術(shù)科技作品競(jìng)賽【三等獎(jiǎng)】(2017.11) 第十三屆“挑戰(zhàn)杯”河南省大學(xué)生課外學(xué)術(shù)科技作品競(jìng)賽【特等獎(jiǎng)】(2017.08)
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