楊林林
發(fā)布時間:2021-01-21 瀏覽次數:

楊林林,男,1989年出生。應用化學博士,副教授,碩士研究生導師。中國化學會會員。目前主要從事超分子化學和熒光探針的生物醫(yī)學應用研究,擅長熒光探針的設計合成及熒光成像應用。主持參與河南省科技廳、河南省教育廳等項目4項,以第一或通訊作者已先后在國際權威SCI期刊發(fā)表論文9篇,其中中科院一區(qū)論文5篇。

 

聯系方式

電話:18336095015

Email:yanglin1989728@163.com

學習經歷

2010/09-2017/06:大連理工大學,應用化學,博士

2006/09-2010:07:大連理工大學,應用化學,學士

工作經歷

2023/03-至今:新鄉(xiāng)醫(yī)學院,法醫(yī)學院,副教授

2017/07-2023/02:新鄉(xiāng)醫(yī)學院,法醫(yī)學院,講師

研究方向

熒光探針的設計合成及生物醫(yī)學應用

主要科研工作

1.具體研究領域

小分子熒光探針的生物熒光成像

2.課題資助

(1)河南省科技攻關項目,基于金屬有機籠狀結構的超分子比率熒光探針的構建及在腫瘤成像方面的應用研究,2023.01-2024.12,主持

(2)河南省高等學校重點科研項目,面向高β-立體選擇性Koenigs-Knorr糖基化反應的金屬有機超分子反應器的研究,2021.01-2022.12,主持

3.獲獎成果

科學技術成果:腫瘤靶向小分子熒光前藥的設計合成及應用

4.近期代表性論文

(1)Linlin Yang&, Pengli Gu&, Beining Li, Junwan Li, Aoxiang Fu, Xianyu Gong, Yanmei Huang, Lixia Xie, Liguo Ji, Nana Ma*, Lili Li*, Guangjie He*. A homocysteine-selective fluorescent probe for cell imaging based on substitution-rearrangement process. Dyes and Pigments. 2022, 207: 110802.

(2)Pengli Gu, Lili Li, Aoxiang Fu, Huina Song, Bin Zhao, Lai Wei, Liguo Ji, Wenqiang Li*, Ruiling Zhang, Qingzhi Wang, Guangjie He*,Linlin Yang*. High-performance fluorescence probe for fast and specific visualization of norepinephrine in vivo and depression-like mice. Bioorganic Chemistry. 2023, 131: 106306.

(3)Linlin Yang&, Nan Yang&, Pengli Gu, Yihua Zhang, Xianyu Gong, Shichao Zhang, Junwan Li, Liguo Ji*, Guangjie He*. A novel naphthalimide-based fluorescent probe for the colorimetric and ratiometric detection of SO2 derivatives in biological imaging. Bioorganic Chemistry. 2022,123, 105801.

(4)Linlin Yang*, Nan Yang, Pengli Gu, Chuang Wang, Beining Li, Yihua Zhang, Liguo Ji, Guangjie He*. A novel flavone-based ESIPT ratiometric fluorescent probe for selectivesensing and imaging of hydrogen polysulfides. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2022, 271: 120962.

(5)Linlin Yang*, Yanping Li, Huaxiong Song, Haihua Zhang, Nan Yang, Qian Peng, Liguo Ji, Guangjie He*. A highly sensitive probe based on spiropyran for colorimetric and fluorescent detection of thiophenol in aqueous media. Dyes and Pigments. 2020, 175, 108154.

(6)Linlin Yang&, Pengli Gu&, Aoxiang Fu, Yanbei Xi, Shaoli Cui, Liguo Ji, Lili Li*,Nana Ma, Qingzhi Wang*, Guangjie He*. TPE-based fluorescent probe for dual channel imaging of pH/viscosity and selective visualization of cancer cells and tissues. Talanta. 2023, 265, 124862.

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