楊林林,男,1989年出生。應(yīng)用化學博士,副教授,碩士研究生導師。中國化學會會員。目前主要從事超分子化學和熒光探針的生物醫(yī)學應(yīng)用研究,擅長熒光探針的設(shè)計合成及熒光成像應(yīng)用。主持參與河南省科技廳、河南省教育廳等項目4項,以第一或通訊作者已先后在國際權(quán)威SCI期刊發(fā)表論文9篇,其中中科院一區(qū)論文5篇。
聯(lián)系方式
電話:18336095015
Email:yanglin1989728@163.com
學習經(jīng)歷
2010/09-2017/06:大連理工大學,應(yīng)用化學,博士
2006/09-2010:07:大連理工大學,應(yīng)用化學,學士
工作經(jīng)歷
2023/03-至今:新鄉(xiāng)醫(yī)學院,法醫(yī)學院,副教授
2017/07-2023/02:新鄉(xiāng)醫(yī)學院,法醫(yī)學院,講師
研究方向
熒光探針的設(shè)計合成及生物醫(yī)學應(yīng)用
主要科研工作
1.具體研究領(lǐng)域
小分子熒光探針的生物熒光成像
2.課題資助
(1)河南省科技攻關(guān)項目,基于金屬有機籠狀結(jié)構(gòu)的超分子比率熒光探針的構(gòu)建及在腫瘤成像方面的應(yīng)用研究,2023.01-2024.12,主持
(2)河南省高等學校重點科研項目,面向高β-立體選擇性Koenigs-Knorr糖基化反應(yīng)的金屬有機超分子反應(yīng)器的研究,2021.01-2022.12,主持
3.獲獎成果
科學技術(shù)成果:腫瘤靶向小分子熒光前藥的設(shè)計合成及應(yīng)用
4.近期代表性論文
(1)Linlin Yang&, Pengli Gu&, Beining Li, Junwan Li, Aoxiang Fu, Xianyu Gong, Yanmei Huang, Lixia Xie, Liguo Ji, Nana Ma*, Lili Li*, Guangjie He*. A homocysteine-selective fluorescent probe for cell imaging based on substitution-rearrangement process. Dyes and Pigments. 2022, 207: 110802.
(2)Pengli Gu, Lili Li, Aoxiang Fu, Huina Song, Bin Zhao, Lai Wei, Liguo Ji, Wenqiang Li*, Ruiling Zhang, Qingzhi Wang, Guangjie He*,Linlin Yang*. High-performance fluorescence probe for fast and specific visualization of norepinephrine in vivo and depression-like mice. Bioorganic Chemistry. 2023, 131: 106306.
(3)Linlin Yang&, Nan Yang&, Pengli Gu, Yihua Zhang, Xianyu Gong, Shichao Zhang, Junwan Li, Liguo Ji*, Guangjie He*. A novel naphthalimide-based fluorescent probe for the colorimetric and ratiometric detection of SO2 derivatives in biological imaging. Bioorganic Chemistry. 2022,123, 105801.
(4)Linlin Yang*, Nan Yang, Pengli Gu, Chuang Wang, Beining Li, Yihua Zhang, Liguo Ji, Guangjie He*. A novel flavone-based ESIPT ratiometric fluorescent probe for selectivesensing and imaging of hydrogen polysulfides. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2022, 271: 120962.
(5)Linlin Yang*, Yanping Li, Huaxiong Song, Haihua Zhang, Nan Yang, Qian Peng, Liguo Ji, Guangjie He*. A highly sensitive probe based on spiropyran for colorimetric and fluorescent detection of thiophenol in aqueous media. Dyes and Pigments. 2020, 175, 108154.
(6)Linlin Yang&, Pengli Gu&, Aoxiang Fu, Yanbei Xi, Shaoli Cui, Liguo Ji, Lili Li*,Nana Ma, Qingzhi Wang*, Guangjie He*. TPE-based fluorescent probe for dual channel imaging of pH/viscosity and selective visualization of cancer cells and tissues. Talanta. 2023, 265, 124862.